Clopixol/Clopixol-Acuphase/Clopixol Depot Side Effects

Clopixol/Clopixol Depot: Extrapyramidal syndromes may occur, especially during the early phase of treatment. In most cases, these side effects can be satisfactorily controlled by reduction of dosage and/or antiparkinsonian drugs. Tardive dyskinesias, which can be more or less persistent, may appear in some patients on long-term therapy. Antiparkinsonian drugs do not alleviate these symptoms. Reduction in dosage or, if possible, discontinuation of therapy is recommended.
Psychic: Drowsiness initially.
Autonomic and Cardiovascular: Dry mouth, urinary retention, disturbance of accommodation, constipation, tachycardia, postural hypotension and dizziness.
Liver: Transient mild alterations in liver function tests may occur.
Clopixol-Acuphase: The frequency of unwanted effects is in general low and the severity of the symptoms is most often mild. They are most pronounced the day after the 1st injection and then decrease rapidly.
Extrapyramidal symptoms can be satisfactorily controlled by antiparkinsonian drugs. Occasionally, orthostatic dizziness may occur and reduced salivation of a mild degree has been observed.